alpha Tubulin antibody (acLys401)

Catalog No. ABIN8119673

This Rabbit Polyclonal antibody specifically detects alpha Tubulin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for alpha Tubulin antibody (acLys401) (ABIN8119673)

Target: alpha Tubulin (TUBA1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Tubulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-alpha Tubulin Antibody

Binding Specificity: acLys401

Purpose: Tubulin α (Acetyl Lys401) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat Tubulin α (Acetyl Lys401)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human Tubulin alpha (Acetyl Lys401)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for alpha Tubulin

Target: alpha Tubulin (TUBA1)

Alternative Name: Tubulin alpha

Background:

Synonyms: Tubulin alpha-1A chain (Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain)

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Gene Name: TUBA1A TUBA3

Protein Name: Tubulin α (Acetyl Lys401)

Gene ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics