Apolipoprotein C-II antibody (AA 1-50)

Catalog No. ABIN8119772

This Rabbit Polyclonal antibody specifically detects Apolipoprotein C-II in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Apolipoprotein C-II antibody (AA 1-50) (ABIN8119772)

Target: Apolipoprotein C-II (APOC2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein C-II antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Apolipoprotein C-II Antibody

Binding Specificity: AA 1-50

Purpose: APOC2 Antibody

Specificity: This antibody detects endogenous levels of human APOC2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human APOC2 AA range: 1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Apolipoprotein C-II

Target: Apolipoprotein C-II (APOC2)

Alternative Name: APOC2

Background:

Synonyms: Apolipoprotein C-II (Apo-CII, ApoC-II, Apolipoprotein C2)

Background: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011],

Gene Name: APOC2 APC2

Protein Name: APOC2

Gene ID: 344

UniProt: P02655

Pathways: Lipid Metabolism