Aprataxin antibody (AA 11-60)

Catalog No. ABIN8119779

The Rabbit Polyclonal anti-Aprataxin antibody is suitable to detect Aprataxin in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for Aprataxin antibody (AA 11-60) (ABIN8119779)

Target: Aprataxin (APTX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Aprataxin Antibody

Binding Specificity: AA 11-60

Purpose: APTX Antibody

Specificity: APTX Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX

Background:

Background: aprataxin(APTX) Homo sapiens This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010],

Gene Name: APTX AXA1

Protein Name: Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding