AVPR2 antibody (AA 1-50)

Catalog No. ABIN8119798

The Rabbit Polyclonal anti-AVPR2 antibody (ABIN8119798) specifically detects AVPR2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for AVPR2 antibody (AA 1-50) (ABIN8119798)

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AVPR2 Antibody

Binding Specificity: AA 1-50

Purpose: AVP Receptor V2 Antibody

Specificity: AVP Receptor V2 Polyclonal Antibody detects endogenous levels of AVP Receptor V2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human AVP Receptor V2. at AA range: 1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for AVPR2

Target: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Alternative Name: AVP Receptor V2

Background:

Synonyms: Vasopressin V2 receptor (V2R) (AVPR V2) (Antidiuretic hormone receptor) (Renal-type arginine vasopressin receptor)

Background: This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus

Gene Name: AVPR2

Protein Name: AVP Receptor V2

Gene ID: 554

UniProt: P30518

Pathways: cAMP Metabolic Process