ACTR1B antibody

Catalog No. ABIN8119808

This Rabbit Monoclonal antibody specifically detects ACTR1B in WB, IHC, IF, ICC, IP and FACS. It exhibits reactivity toward Human.

Quick Overview for ACTR1B antibody (ABIN8119808)

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ACTR1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: AB2226

Product Details anti-ACTR1B Antibody

Purpose: ACTR1B Rabbit mAb

Specificity: This antibody detects endogenous levels of ACTR1B protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:•100-1:300 | IF, 1:100-1:300 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | FC, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for ACTR1B

Target: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Alternative Name: ACTR1B

Background:

Synonyms: ACTR1B, CTRN2, Beta-centractin , Actin-related protein 1B, ARP1B,

Background: This gene encodes a 42. 3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],

Gene Name: ACTR1B, CTRN2

Protein Name: ACTR1B

Gene ID: 10120

UniProt: P42025