ARP1B antibody, CTRN2 antibody, PC3 antibody, 2310066K23Rik antibody, AA960180 antibody, AI851923 antibody, Arp1b antibody, ACTR1B antibody, ARP1 actin related protein 1 homolog B antibody, ARP1 actin-related protein 1B, centractin beta antibody, ARP1 actin-related protein 1 homolog B antibody, ARP1 actin-related protein 1 homolog B, centractin beta (yeast) antibody, beta-centractin antibody, ACTR1B antibody, Actr1b antibody, LOC100594459 antibody
Background
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.,ACTR1B,ARP1B,CTRN2,PC3,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microfilaments,Motor Proteins,ACTR1B