ATG5 antibody

Catalog No. ABIN8119848

The Rabbit Polyclonal anti-ATG5 antibody is suitable to detect ATG5 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for ATG5 antibody (ABIN8119848)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATG5 Antibody

Purpose: ATG5 Antibody

Specificity: The antibody detects endogenous ATG5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of ATG5

Isotype: IgG

Application Details

Application Notes: IHC 1:50-300,WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name: ATG5

Background:

Synonyms: Autophagy protein 5 (APG5-like, Apoptosis-specific protein)

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015],

Gene Name: ATG5 APG5L ASP

Protein Name: Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)

Gene ID: 9494

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy