BCL3 antibody (AA 340-420)

Catalog No. ABIN8119945

The Rabbit Polyclonal anti-BCL3 antibody (ABIN8119945) specifically detects BCL3 in WB, IHC and IF. The antibody is reactive with Human, Mouse, Rat and Goat samples.

Quick Overview for BCL3 antibody (AA 340-420) (ABIN8119945)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivity: Human, Mouse, Rat, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BCL3 Antibody

Binding Specificity: AA 340-420

Purpose: BCL3 Antibody

Specificity: BCL3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IF 1:50-200. IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Alternative Name: BCL3

Background:

Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia.The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],

Gene Name: BCL3 BCL4 D19S37

Protein Name: B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)

Gene ID: 602

UniProt: P20749

Pathways: NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus