BIRC2 antibody

Catalog No. ABIN8119952

This Rabbit Polyclonal antibody specifically detects BIRC2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for BIRC2 antibody (ABIN8119952)

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BIRC2 Antibody

Purpose: BIRC2 Antibody

Specificity: BIRC2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Alternative Name: BIRC2

Background:

Background: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: BIRC2 API1 IAP2 MIHB RNF48

Protein Name: Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)

Gene ID: 329

UniProt: Q13490

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades