BLOC1S1 antibody (AA 50-130)

Catalog No. ABIN8119999

The Rabbit Polyclonal anti-BLOC1S1 antibody (ABIN8119999) specifically detects BLOC1S1 in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for BLOC1S1 antibody (AA 50-130) (ABIN8119999)

Target: BLOC1S1 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-BLOC1S1 Antibody

Binding Specificity: AA 50-130

Purpose: RT14 Antibody

Specificity: RT14 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BLOC1S1

Target: BLOC1S1 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1))

Alternative Name: RT14

Background:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010],

Gene Name: MRPS14

Protein Name: 28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt)

Gene ID: 63931

UniProt: O60783