BMP10 antibody (AA 361-410)

Catalog No. ABIN8120008

The Rabbit Polyclonal anti-BMP10 antibody (ABIN8120008) specifically detects BMP10 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BMP10 antibody (AA 361-410) (ABIN8120008)

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMP10 Antibody

Binding Specificity: AA 361-410

Purpose: BMP-10 Antibody

Specificity: BMP-10 Polyclonal Antibody detects endogenous levels of BMP-10

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from BMP-10 at AA range: 361-410

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Alternative Name: BMP-10

Background:

Synonyms: bone morphogenetic protein 10

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016],

Gene Name: BMP10

Protein Name: BMP-10

Gene ID: 27302

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation