BRSK2 antibody (pThr260)

Catalog No. ABIN8120018

This Rabbit Polyclonal antibody specifically detects BRSK2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BRSK2 antibody (pThr260) (ABIN8120018)

Target: BRSK2 (BR serine/threonine Kinase 2 (BRSK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRSK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRSK2 Antibody

Binding Specificity: pThr260

Purpose: BRSK2 (Phospho Thr260) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat BRSK2 (Phospho Thr260)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human BRSK2 (Phospho Thr260)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BRSK2

Target: BRSK2 (BR serine/threonine Kinase 2 (BRSK2))

Alternative Name: BRSK2

Background:

Synonyms: Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1, Brain-selective kinase 2, EC 2.7.11.26, Brain-specific serine/threonine-protein kinase 2, BR serine/threonine-protein kinase 2, Serine/threonine-protein kinase 29, Serine/threonine-protein kinase SAD-A)

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,

Gene Name: BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12

Protein Name: BRSK2 (Phospho Thr260)

Gene ID: 9024

UniProt: Q8IWQ3