BTN3A1/2/3 antibody (AA 41-90)

Catalog No. ABIN8120052

The Rabbit Polyclonal anti-BTN3A1/2/3 antibody is suitable to detect BTN3A1/2/3 in samples from Human, Mouse and Rat. It has been validated for ELISA, IF and IHC.

Quick Overview for BTN3A1/2/3 antibody (AA 41-90) (ABIN8120052)

Target: BTN3A1/2/3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTN3A1/2/3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-BTN3A1/2/3 Antibody

Binding Specificity: AA 41-90

Purpose: BTN3A1/2/3 Antibody

Specificity: The antibody detects endogenous BTN3A1/2/3

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 41-90

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BTN3A1/2/3

Target: BTN3A1/2/3

Background:

Background: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1, MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010],

Gene Name: BTN3A1/2/3 BTF3/4/5

Protein Name: Butyrophilin subfamily 3 member A1/2/3 (CD antigen CD277)

Gene ID: 11119

UniProt: O00481