CAMLG antibody

Catalog No. ABIN8120132

This Rabbit Polyclonal antibody specifically detects CAMLG in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CAMLG antibody (ABIN8120132)

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CAMLG Antibody

Purpose: CAMLG Antibody

Specificity: CAMLG Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CAMLG

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Alternative Name: CAMLG

Background:

Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin.The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],

Gene Name: CAMLG CAML

Protein Name: Calcium signal-modulating cyclophilin ligand (CAML)

Gene ID: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway