Caldesmon antibody (AA 100-200)

Catalog No. ABIN8120144

This Mouse Monoclonal antibody specifically detects Caldesmon in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for Caldesmon antibody (AA 100-200) (ABIN8120144)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1280

Product Details anti-Caldesmon Antibody

Binding Specificity: AA 100-200

Purpose: Caldesmon mouse mAb

Specificity: The antibody can recognize human h-caldesmon and l-caldesmon protein. In western blotting, the antibody labels a 93 kDa band.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Caldesmon protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: Caldesmon

Background:

Synonyms: CAD, CALD 1, CALD1, CALD1_HUMAN, Caldesmon 1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, Caldesmon, Caldesmon1, CDM, H CAD, HCAD, L CAD, LCAD, MGC21352, NAG22

Background: Caldesmon is a binding protein of smooth muscle actin and calmodulin. It is a cytoskeleton related protein with the function of regulating smooth muscle contraction. In clinical diagnosis, it is used to label smooth muscle cells and cells with smooth muscle differentiation, identify myofibroblastoma from true leiomyoma, and combine CD10 to identify endometrial stromal sarcoma and uterine smooth muscle tumor.

Gene Name: CALD1

Protein Name: Caldesmon

Gene ID: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction