CA9 antibody

Catalog No. ABIN8120183

This Mouse Monoclonal antibody specifically detects CA9 in IHC. It exhibits reactivity toward Human.

Quick Overview for CA9 antibody (ABIN8120183)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB2460

Product Details anti-CA9 Antibody

Purpose: CA IX mouse mAb

Specificity: The antibody can specifically recognize human CA IX protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: Recombinant protein of the human CA IX protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: CA IX

Background:

Synonyms: G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1

Background: CA IX (Carbonic Anhydrase IX) is a transmembrane protein belonging to the carbonic anhydrase family. It catalyzes the conversion of carbon dioxide and water into bicarbonate and protons in the extracellular environment. CA IX is minimally expressed in normal tissues, primarily found in gastrointestinal epithelial cells, but is highly expressed in various malignant tumors, such as clear cell renal carcinoma, breast cancer, and pancreatic cancer. Its expression is significantly upregulated under hypoxic conditions. Therefore, CA IX has been widely studied as a tumor biomarker and a potential therapeutic target.

Gene Name: CA9

Protein Name: CA IX

Gene ID: 768

UniProt: Q16790