CPT1C antibody (Cleaved-Ala114, Heavy Chain)

Catalog No. ABIN8120211

The Rabbit Polyclonal anti-CPT1C antibody is suitable to detect CPT1C in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CPT1C antibody (Cleaved-Ala114, Heavy Chain) (ABIN8120211)

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CPT1C Antibody

Binding Specificity: Cleaved-Ala114, Heavy Chain

Purpose: CATL1 (heavy chain, Cleaved-Ala114) Antibody

Specificity: This antibody detects endogenous levels of Human CATL1 (heavy chain, Cleaved-Ala114, protein was cleaved amino acid sequence between 113-114 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human CATL1 (heavy chain, Cleaved-Ala114)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Alternative Name: CATL1

Background:

Synonyms: Cathepsin L1 (EC 3.4.22.15, Major excreted protein, MEP) [Cleaved into: Cathepsin L1 heavy chain, Cathepsin L1 light chain]

Background: catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,

Gene Name: CTSL1 CTSL

Protein Name: CATL1 (heavy chain, Cleaved-Ala114)

Gene ID: 1514

UniProt: P07711

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process