CTSA antibody (Cleaved-Met327)

Catalog No. ABIN8120272

The Rabbit Polyclonal anti-CTSA antibody (ABIN8120272) specifically detects CTSA in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for CTSA antibody (Cleaved-Met327) (ABIN8120272)

Target: CTSA (Cathepsin A (CTSA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTSA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTSA Antibody

Binding Specificity: Cleaved-Met327

Purpose: PPGB (20k, Cleaved-Met327) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse PPGB (20k, Cleaved-Met327, protein was cleaved amino acid sequence between 326-327 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CTSA

Target: CTSA (Cathepsin A (CTSA))

Alternative Name: PPGB

Background:

Synonyms: Lysosomal protective protein (EC 3.4.16.5, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain, Lysosomal protective protein 20 kDa chain]

Background: catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain, disulfide-linked.,

Gene Name: CTSA PPGB

Protein Name: PPGB (20k, Cleaved-Met327)

Gene ID: 5476

UniProt: P10619