RAD1 antibody

Catalog No. ABIN8120438

This Rabbit Polyclonal antibody specifically detects RAD1 in WB, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for RAD1 antibody (ABIN8120438)

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAD1 Antibody

Purpose: RAD1 Antibody

Specificity: This antibody detects endogenous levels of human RAD1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human RAD1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RAD1

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Alternative Name: RAD1

Background:

Synonyms: Cell cycle checkpoint protein RAD1 (hRAD1, EC 3.1.11.2, DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein)

Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009],

Gene Name: RAD1 REC1

Protein Name: RAD1

Gene ID: 5810

UniProt: O60671

Pathways: M Phase