CENPM antibody (AA 30-110)

Catalog No. ABIN8120458

The Rabbit Polyclonal anti-CENPM antibody (ABIN8120458) specifically detects CENPM in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CENPM antibody (AA 30-110) (ABIN8120458)

Target: CENPM (Centromere Protein M (CENPM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CENPM Antibody

Binding Specificity: AA 30-110

Purpose: CENP-M Antibody

Specificity: This antibody detects endogenous levels of human CENP-M

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CENP-M AA range: 30-110

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CENPM

Target: CENPM (Centromere Protein M (CENPM))

Alternative Name: CENP-M

Background:

Synonyms: Centromere protein M (CENP-M, Interphase centromere complex protein 39, Proliferation-associated nuclear element protein 1)

Background: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: CENPM C22orf18 ICEN39 PANE1

Protein Name: CENP-M

Gene ID: 79019

UniProt: Q9NSP4