CLCN1 antibody

Catalog No. ABIN8120516

This Rabbit Polyclonal antibody specifically detects CLCN1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CLCN1 antibody (ABIN8120516)

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLCN1 Antibody

Purpose: CLCN1 Antibody

Specificity: CLCN1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CLCN1

Target: CLCN1 (Chloride Channel 1, Skeletal Muscle (CLCN1))

Alternative Name: CLCN1

Background:

Background: chloride voltage-gated channel 1(CLCN1) Homo sapiens The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology.The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],

Gene Name: CLCN1 CLC1

Protein Name: Chloride channel protein 1 (ClC-1) (Chloride channel protein, skeletal muscle)

Gene ID: 1180

UniProt: P35523