CNTF antibody

Catalog No. ABIN8120580

The Rabbit Polyclonal anti-CNTF antibody is suitable to detect CNTF in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for CNTF antibody (ABIN8120580)

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNTF Antibody

Purpose: CNTF Antibody

Specificity: CNTF protein(A218) detects endogenous levels of CNTF

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of CNTF

Isotype: IgG

Application Details

Application Notes: WB 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CNTF

Target: CNTF (Ciliary Neurotrophic Factor (CNTF))

Alternative Name: CNTF

Background:

Synonyms: CNTF, Ciliary neurotrophic factor, CNTF

Background: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010],

Gene Name: CNTF

Protein Name: Ciliary neurotrophic factor (CNTF)

Gene ID: 1270

UniProt: P26441

Pathways: JAK-STAT Signaling