Claudin 2 antibody (AA 150-230)

Catalog No. ABIN8120601

The Mouse Monoclonal anti-Claudin 2 antibody is suitable to detect Claudin 2 in samples from Human. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Claudin 2 antibody (AA 150-230) (ABIN8120601)

Target: Claudin 2 (CLDN2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Claudin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1846

Product Details anti-Claudin 2 Antibody

Binding Specificity: AA 150-230

Purpose: Claudin 2 mouse mAb

Specificity: This antibody detects endogenous levels of Claudin 2 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 230 of the human Claudin 2 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: Claudin 2

Background:

Synonyms: Claudin-2, SP82, CLDN2

Background: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010],

Gene Name: CLDN2

Protein Name: Claudin 2

Gene ID: 9075

UniProt: P57739

Pathways: Hepatitis C