C8A antibody (AA 201-250)

Catalog No. ABIN8120715

The Rabbit Polyclonal anti-C8A antibody is suitable to detect C8A in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for C8A antibody (AA 201-250) (ABIN8120715)

Target: C8A (Complement Component 8, alpha Polypeptide (C8A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-C8A Antibody

Binding Specificity: AA 201-250

Purpose: C8 α Antibody

Specificity: C8 α Polyclonal Antibody detects endogenous levels of C8 α

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human C8 alpha. at AA range: 201-250

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for C8A

Target: C8A (Complement Component 8, alpha Polypeptide (C8A))

Alternative Name: C8 alpha

Background:

Synonyms: Complement component C8 alpha chain (Complement component 8 subunit alpha)

Background: C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma.This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008],

Gene Name: C8A

Protein Name: C8 α

Gene ID: 731

UniProt: P07357

Pathways: Complement System