Adipsin antibody (AA 101-150)

Catalog No. ABIN8120720

This Rabbit Polyclonal antibody specifically detects Adipsin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Adipsin antibody (AA 101-150) (ABIN8120720)

Target: Adipsin (CFD) (Complement Factor D (CFD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adipsin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Adipsin Antibody

Binding Specificity: AA 101-150

Purpose: Adipsin Antibody

Specificity: This antibody detects endogenous levels of Human Adipsin

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Adipsin AA range: 101-150

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Adipsin

Target: Adipsin (CFD) (Complement Factor D (CFD))

Alternative Name: Adipsin

Background:

Synonyms: Complement factor D (EC 3.4.21.46, Adipsin, C3 convertase activator, Properdin factor D)

Background: catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,

Gene Name: CFD DF PFD

Protein Name: Adipsin

Gene ID: 1675

UniProt: P00746

Pathways: Complement System