CFHR5 antibody (AA 353-403)

Catalog No. ABIN8120724

The Rabbit Polyclonal anti-CFHR5 antibody is suitable to detect CFHR5 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for CFHR5 antibody (AA 353-403) (ABIN8120724)

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR5 Antibody

Binding Specificity: AA 353-403

Purpose: FHR5 Antibody

Specificity: This antibody detects endogenous levels of FHR5 at Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FHR5 AA range: 353-403

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Alternative Name: FHR5

Background:

Synonyms: Complement factor H-related protein 5 (FHR-5)

Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation.The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],

Gene Name: CFHR5 CFHL5 FHR5

Protein Name: FHR5

Gene ID: 81494

UniProt: Q9BXR6