COX1 antibody (AA 483-533)

Catalog No. ABIN8120860

The Rabbit Polyclonal anti-COX1 antibody (ABIN8120860) specifically detects COX1 in WB. The antibody is reactive with Human samples.

Quick Overview for COX1 antibody (AA 483-533) (ABIN8120860)

Target: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX1 Antibody

Binding Specificity: AA 483-533

Purpose: COX1 Antibody

Specificity: The antibody detects endogenous COX1 proteins.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of COX1 AA range: 483-533

Isotype: IgG

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COX1

Target: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Alternative Name: COX1

Background:

Synonyms: PTGS1, COX1, Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1

Background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Gene Name: PTGS1

Protein Name: Prostaglandin G/H synthase 1

Gene ID: 5742

UniProt: P23219

Pathways: Proton Transport