DAP Kinase 1 antibody (pSer308)

Catalog No. ABIN8120940

The Rabbit Polyclonal anti-DAP Kinase 1 antibody is suitable to detect DAP Kinase 1 in samples from Human and Mouse. It has been validated for WB, IHC and IF.

Quick Overview for DAP Kinase 1 antibody (pSer308) (ABIN8120940)

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAP Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DAP Kinase 1 Antibody

Binding Specificity: pSer308

Purpose: DAPK1 (Phospho Ser308) Antibody

Specificity: This antibody detects endogenous phospho levels of DAPK1 (Phospho-Ser308) at Human:S308, Mouse:S308

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human DAPK1 (Phospho-Ser308)

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DAP Kinase 1

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Alternative Name: DAPK1

Background:

Synonyms: Death-associated protein kinase 1 (DAP kinase 1, EC 2.7.11.1)

Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Gene Name: DAPK1 DAPK

Protein Name: DAPK1 (Phospho-Ser308)

Gene ID: 1612

UniProt: P53355

Pathways: MAPK Signaling, Interferon-gamma Pathway