DGCR8 antibody (AA 467-517)

Catalog No. ABIN8120988

The Rabbit Polyclonal anti-DGCR8 antibody is suitable to detect DGCR8 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for DGCR8 antibody (AA 467-517) (ABIN8120988)

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DGCR8 Antibody

Binding Specificity: AA 467-517

Purpose: DGCR8 Antibody

Specificity: This antibody detects endogenous levels of DGCR8 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DGCR8 AA range: 467-517

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DGCR8

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Alternative Name: DGCR8

Background:

Synonyms: Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)

Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

Gene Name: DGCR8 C22orf12 DGCRK6 LP4941

Protein Name: DGCR8

Gene ID: 54487

UniProt: Q8WYQ5

Pathways: Regulatory RNA Pathways