DAB1 antibody (pTyr220)

Catalog No. ABIN8121007

The Rabbit Polyclonal anti-DAB1 antibody (ABIN8121007) specifically detects DAB1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DAB1 antibody (pTyr220) (ABIN8121007)

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DAB1 Antibody

Binding Specificity: pTyr220

Purpose: Dab1 (Phospho Tyr220) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat Dab1 (Phospho Tyr220)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human Dab1 (Phospho Tyr220)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Alternative Name: Dab1

Background:

Synonyms: DAB1, Disabled homolog 1

Background: domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,

Gene Name: DAB1

Protein Name: Dab1 (Phospho Tyr220)

Gene ID: 1600

UniProt: O75553