DISC1 antibody (AA 423-473)

Catalog No. ABIN8121023

This Rabbit Polyclonal antibody specifically detects DISC1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DISC1 antibody (AA 423-473) (ABIN8121023)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DISC1 Antibody

Binding Specificity: AA 423-473

Purpose: DISC1 Antibody

Specificity: This antibody detects endogenous levels of DISC1 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DISC1 AA range: 423-473

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: DISC1

Background:

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: DISC1 KIAA0457

Protein Name: DISC1

Gene ID: 27185

UniProt: Q9NRI5

Pathways: Regulation of Cell Size