Dystrophin antibody

Catalog No. ABIN8121097

The Rabbit Monoclonal anti-Dystrophin antibody (Clone AB2266) (ABIN8121097) specifically detects Dystrophin in IHC, WB, ELISA, IP and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Dystrophin antibody (ABIN8121097)

Target: Dystrophin (DMD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Dystrophin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB2266

Product Details anti-Dystrophin Antibody

Purpose: Dystrophin Rabbit mAb

Specificity: This antibody detects endogenous levels of Dystrophin protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Dystrophin

Target: Dystrophin (DMD)

Alternative Name: Dystrophin

Background:

Synonyms: Dystrophin

Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC) , which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD) , Becker muscular dystrophy (BMD) , or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Gene Name: DMD

Protein Name: Dystrophin

Gene ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development