EPH Receptor A4 antibody (pTyr596)

Catalog No. ABIN8121213

The Rabbit Polyclonal anti-EPH Receptor A4 antibody is suitable to detect EPH Receptor A4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for EPH Receptor A4 antibody (pTyr596) (ABIN8121213)

Target: EPH Receptor A4 (EPHA4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPH Receptor A4 Antibody

Binding Specificity: pTyr596

Purpose: EphA4 (phospho Tyr596) Antibody

Specificity: Phospho-EphA4 (Y596) Polyclonal Antibody detects endogenous levels of EphA4 protein only when phosphorylated at Y596.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human EphA4 (phospho Tyr596)

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Alternative Name: EphA4

Background:

Synonyms: EPHA4, HEK8, SEK, TYRO1, Ephrin type-A receptor 4, EPH-like kinase 8, EK8, hEK8, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],

Gene Name: EPHA4

Protein Name: Ephrin type-A receptor 4

Gene ID: 2043

UniProt: P54764

Pathways: RTK Signaling