EXTL3 antibody

Catalog No. ABIN8121337

The Rabbit Polyclonal anti-EXTL3 antibody (ABIN8121337) specifically detects EXTL3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for EXTL3 antibody (ABIN8121337)

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EXTL3 Antibody

Purpose: EXTL3 Antibody

Specificity: EXTL3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3

Background:

Background: This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012],

Gene Name: EXTL3 EXTL1L EXTR1 KIAA0519

Protein Name: Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3)

Gene ID: 2137

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling