FBXW11 antibody (AA 464-514)

Catalog No. ABIN8121351

The Rabbit Polyclonal anti-FBXW11 antibody is suitable to detect FBXW11 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for FBXW11 antibody (AA 464-514) (ABIN8121351)

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXW11 Antibody

Binding Specificity: AA 464-514

Purpose: FBW1B Antibody

Specificity: This antibody detects endogenous levels of FBW1B at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FBW1B AA range: 464-514

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FBXW11

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Alternative Name: FBW1B

Background:

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008],

Gene Name: FBXW11 BTRCP2 FBW1B FBXW1B KIAA0696

Protein Name: FBW1B

Gene ID: 23291

UniProt: Q9UKB1