FAM111A antibody (AA 264-314)

Catalog No. ABIN8121365

This Rabbit Polyclonal antibody specifically detects FAM111A in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for FAM111A antibody (AA 264-314) (ABIN8121365)

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM111A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM111A Antibody

Binding Specificity: AA 264-314

Purpose: F111A Antibody

Specificity: This antibody detects endogenous levels of F111A at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human F111A AA range: 264-314

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FAM111A

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Alternative Name: F111A

Background:

Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: FAM111A KIAA1895

Protein Name: F111A

Gene ID: 63901

UniProt: Q96PZ2