Fascin antibody (AA 250-350)

Catalog No. ABIN8121391

The Rabbit Monoclonal anti-Fascin antibody (Clone AB1267) (ABIN8121391) specifically detects Fascin in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Fascin antibody (AA 250-350) (ABIN8121391)

Target: Fascin (FSCN1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1267

Product Details anti-Fascin Antibody

Binding Specificity: AA 250-350

Purpose: Fascin Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human Fascin protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 250 - 350 of the human Fascin protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background:

Synonyms: 55 kDa actin bundling protein,55 kDa actin-bundling protein,Actin bundling protein,actin bundling protein, 55-KD,FAN 1,FAN1,Fascin 1,Fascin actin bundling protein 1,Fascin,Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuRatus) ,Fascin homolog 1,Fascin, sea urchin, homolog of, 1,Fascin1,FLJ38511,FSCN 1,FSCN1,FSCN1_HUMAN,HSN,p55,Singed (Drosophila) like (sea urchin fascin homolog like) ,Singed drosophila homolog like,Singed like (fascin homolog sea urchin) (Drosophila) ,Singed like (fascin homolog sea urchin) ,Singed like protein,Singed, drosophila, homolog of,Singed-like protein,SNL,Strongylocentrotus purpuRatus

Background: Fascin is a highly conserved actin bundle protein, which is located in microfilaments and stress fibers involved in microfilament bundle formation. It is mainly expressed in dendritic cells and is a sensitive marker of R- S cells. Lymphocytes, plasma cells and myeloid cells did not express. It can be used to diagnose Hodgkin's lymphoma and Langerhans cell histiocytosis.

Gene Name: FSCN1

Protein Name: Fascin

Gene ID: 6624

UniProt: Q16658