Fascin antibody (AA 250-350)

Catalog No. ABIN8121392

This Mouse Monoclonal antibody specifically detects Fascin in IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Fascin antibody (AA 250-350) (ABIN8121392)

Target: Fascin (FSCN1)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1541

Product Details anti-Fascin Antibody

Binding Specificity: AA 250-350

Purpose: Fascin Mouse mAb (Ready to Use)

Specificity: The antibody can specifically recognize human Fascin protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 250 - 350 of the human Fascin protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background:

Synonyms: 55 kDa actin bundling protein, 55 kDa actin-bundling protein, Actin bundling protein, actin bundling protein, 55-KD, FAN 1, FAN1, Fascin 1, Fascin actin bundling protein 1, Fascin, Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuRatus) , Fascin homolog 1, Fascin, sea urchin, homolog of, 1, Fascin1, FLJ38511, FSCN 1, FSCN1, FSCN1_HUMAN, HSN, p55, Singed (Drosophila) like (sea urchin fascin homolog like) , Singed drosophila homolog like, Singed like (fascin homolog sea urchin) (Drosophila) , Singed like (fascin homolog sea urchin) , Singed like protein, Singed, drosophila, homolog of, Singed-like protein, SNL, Strongylocentrotus purpuRatus

Background: Fascin is a highly conserved actin bundle protein, which is located in microfilaments and stress fibers involved in microfilament bundle formation. It is mainly expressed in dendritic cells and is a sensitive marker of R- S cells. Lymphocytes, plasma cells and myeloid cells did not express. It can be used to diagnose Hodgkin's lymphoma and Langerhans cell histiocytosis.

Gene Name: FSCN1

Protein Name: Fascin

Gene ID: 6624

UniProt: Q16658