Fascin antibody

Catalog No. ABIN8121394

The Rabbit Monoclonal anti-Fascin antibody (Clone AB1621) (ABIN8121394) specifically detects Fascin in WB, IHC, IF, ELISA and IP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Fascin antibody (ABIN8121394)

Target: Fascin (FSCN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Clone: AB1621

Product Details anti-Fascin Antibody

Purpose: Fascin Rabbit mAb

Specificity: This antibody detects endogenous levels of Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:10000-1:20000 | IHC, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background:

Synonyms: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Gene Name: FSCN1 FAN1 HSN SNL

Protein Name: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Gene ID: 6624

UniProt: Q16658