FES antibody (pTyr713)

Catalog No. ABIN8121416

This Rabbit Polyclonal antibody specifically detects FES in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FES antibody (pTyr713) (ABIN8121416)

Target: FES (Feline Sarcoma Oncogene (FES))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FES antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FES Antibody

Binding Specificity: pTyr713

Purpose: c-Fes (Phospho Tyr713) Antibody

Specificity: This antibody detects endogenous levels of c-Fes (Phospho-Tyr713) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human c-Fes (Phospho-Tyr713)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FES

Target: FES (Feline Sarcoma Oncogene (FES))

Alternative Name: c-Fes

Background:

Synonyms: Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)

Background: This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009],

Gene Name: FES FPS

Protein Name: c-Fes (Phospho-Tyr713)

Gene ID: 2242

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2