Fibrinogen beta Chain antibody

Catalog No. ABIN8121432

The Rabbit Polyclonal anti-Fibrinogen beta Chain antibody is suitable to detect Fibrinogen beta Chain in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Fibrinogen beta Chain antibody (ABIN8121432)

Target: Fibrinogen beta Chain (FGB)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fibrinogen beta Chain Antibody

Purpose: Fibrinogen β Antibody

Specificity: Fibrinogen β Polyclonal Antibody detects endogenous levels of Fibrinogen β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Fibrinogen beta.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: Fibrinogen beta

Background:

Synonyms: FGB, Fibrinogen beta chain

Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],

Gene Name: FGB

Protein Name: Fibrinogen beta chain

Gene ID: 2244

UniProt: P02675