FGFRL1 antibody (AA 130-210)

Catalog No. ABIN8121448

The Rabbit Polyclonal anti-FGFRL1 antibody (ABIN8121448) specifically detects FGFRL1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for FGFRL1 antibody (AA 130-210) (ABIN8121448)

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFRL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FGFRL1 Antibody

Binding Specificity: AA 130-210

Purpose: FGFR-5 Antibody

Specificity: FGFR-5 Polyclonal Antibody detects endogenous levels of FGFR-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from FGFR-5 . at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FGFRL1

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Alternative Name: FGFR-5

Background:

Synonyms: FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5

Background: The protein encoded byThis gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other

Gene Name: FGFRL1

Protein Name: Fibroblast growth factor receptor-like 1

Gene ID: 53834

UniProt: Q8N441

Pathways: RTK Signaling