FKBP1B antibody (AA 35-85)

Catalog No. ABIN8121464

This Rabbit Polyclonal antibody specifically detects FKBP1B in IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FKBP1B antibody (AA 35-85) (ABIN8121464)

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP1B antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-FKBP1B Antibody

Binding Specificity: AA 35-85

Purpose: FKBP1B Antibody

Specificity: This antibody detects endogenous levels of human FKBP1B

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FKBP1B AA range: 35-85

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA(peptide)1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: FKBP1B

Background:

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B, EC 5.2.1.8, 12.6 kDa FK506-binding protein, 12.6 kDa FKBP, FKBP-12.6, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP12.6, Rotamase, h-FKBP-12)

Background: The protein encoded byThis gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4

Protein Name: FKBP1B

Gene ID: 2281

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity