GGT1 antibody (Cleaved-Thr381, Light Chain)

Catalog No. ABIN8121585

The Rabbit Polyclonal anti-GGT1 antibody is suitable to detect GGT1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GGT1 antibody (Cleaved-Thr381, Light Chain) (ABIN8121585)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GGT1 Antibody

Binding Specificity: Cleaved-Thr381, Light Chain

Purpose: GGT1 (light chain, Cleaved-Thr381) Antibody

Specificity: This antibody detects endogenous levels of Human GGT1 (light chain, Cleaved-Thr381, protein was cleaved amino acid sequence between 380-381 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human GGT1 (light chain, Cleaved-Thr381)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1

Background:

Synonyms: Gamma-glutamyltranspeptidase 1 (GGT 1, EC 2.3.2.2, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, EC 3.4.19.13, Leukotriene-C4 hydrolase, EC 3.4.19.14, CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain]

Background: The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014],

Gene Name: GGT1 GGT

Protein Name: GGT1 (light chain, Cleaved-Thr381)

Gene ID: 2678

UniProt: P19440