GABRE antibody

Catalog No. ABIN8121589

The Rabbit Polyclonal anti-GABRE antibody (ABIN8121589) specifically detects GABRE in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GABRE antibody (ABIN8121589)

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRE Antibody

Purpose: GABAA Rε Antibody

Specificity: GABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GABAA range: Repsilon.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GABRE

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Alternative Name: GABAA Repsilon

Background:

Synonyms: GABRE, Gamma-aminobutyric acid receptor subunit epsilon, GABA(A) receptor subunit epsilon

Background: The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system.This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008],

Gene Name: GABRE

Protein Name: Gamma-aminobutyric acid receptor subunit epsilon

Gene ID: 2564

UniProt: P78334

Pathways: Synaptic Membrane