GABBR2 antibody (pSer893)

Catalog No. ABIN8121591

The Rabbit Polyclonal anti-GABBR2 antibody is suitable to detect GABBR2 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for GABBR2 antibody (pSer893) (ABIN8121591)

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABBR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABBR2 Antibody

Binding Specificity: pSer893

Purpose: GABBR2 (Phospho Ser893) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat GABBR2 (Phospho Ser893)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human GABBR2 (Phospho Ser893)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GABBR2

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Alternative Name: GABBR2

Background:

Synonyms: Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20)

Background: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],

Gene Name: GABBR2 GPR51 GPRC3B

Protein Name: GABBR2 (Phospho Ser893)

Gene ID: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process