Gephyrin antibody

Catalog No. ABIN8121639

The Rabbit Polyclonal anti-Gephyrin antibody is suitable to detect Gephyrin in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Gephyrin antibody (ABIN8121639)

Target: Gephyrin (GPHN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Gephyrin Antibody

Purpose: GEPH Antibody

Specificity: GEPH Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: GEPH

Background:

Background: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008],

Gene Name: GPHN GPH KIAA1385

Protein Name: Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G)Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]

Gene ID: 10243

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development