GSTM5 antibody (AA 99-149)

Catalog No. ABIN8121723

The Rabbit Polyclonal anti-GSTM5 antibody is suitable to detect GSTM5 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for GSTM5 antibody (AA 99-149) (ABIN8121723)

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSTM5 Antibody

Binding Specificity: AA 99-149

Purpose: GSTM5 Antibody

Specificity: This antibody detects endogenous levels of GSTM5 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GSTM5 AA range: 99-149

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Alternative Name: GSTM5

Background:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008],

Gene Name: GSTM5

Protein Name: GSTM5

Gene ID: 2949

UniProt: P46439