Glycogen Synthase 1 antibody (pSer641)

Catalog No. ABIN8121751

The Rabbit Polyclonal anti-Glycogen Synthase 1 antibody (ABIN8121751) specifically detects Glycogen Synthase 1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Glycogen Synthase 1 antibody (pSer641) (ABIN8121751)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: pSer641

Purpose: Glycogen Synthase 1 (phospho Ser641) Antibody

Specificity: Phospho-Glycogen Synthase 1 (S641) Polyclonal Antibody detects endogenous levels of Glycogen Synthase 1 protein only when phosphorylated at S641.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Glycogen Synthase 1 (phospho Ser641)

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: Glycogen Synthase 1

Background:

Synonyms: GYS1, GYS, Glycogen [starch] synthase, muscle

Background: The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],

Gene Name: GYS1

Protein Name: Glycogen [starch] synthase muscle

Gene ID: 2997

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process