GP6 antibody

Catalog No. ABIN8121771

The Rabbit Polyclonal anti-GP6 antibody is suitable to detect GP6 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for GP6 antibody (ABIN8121771)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GP6 Antibody

Purpose: GPVI Antibody

Specificity: GPVI Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein. AA 21-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: GPVI

Background:

Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Gene Name: GP6

Protein Name: Platelet glycoprotein VI (GPVI) (Glycoprotein 6)

Gene ID: 51206

UniProt: Q9HCN6